PIM Kinase: A Potential Drug Target (P19722)

Target Name: Pim Kinase

NCBI ID: P19722

Pim Kinase

Other Name(s): PIM

PIM Kinase: A Potential Drug Target

Pim Kinase (PIM) is a protein that plays a crucial role in various cellular processes. It is a subunit of the protein kinase kinase A (PKA), which is an essential enzyme involved in cell signaling pathways. PIM is a 21-kDa protein that is highly conserved, with 19% identity at the amino acid level. It is expressed in most tissues and cells and is involved in various cellular processes, including cell signaling, DNA replication, and cell cycle progression.

PIM is a well-known protein that has been studied extensively, both in its function and its potential as a drug target. Its function in cell signaling pathways is crucial in the regulation of various cellular processes, including cell proliferation, differentiation, and survival.

One of the well-known functions of PIM is its role in cell proliferation. PIM is involved in the regulation of cell cycle progression, which is the process by which cells grow, divide, and replicate their genetic material. PIM plays a crucial role in the G1 phase of the cell cycle, where cell growth and preparation for cell division are regulated.

In addition to its role in cell proliferation, PIM is also involved in the regulation of cell differentiation and survival. PIM has been shown to be involved in the regulation of cell adhesion, which is the process by which cells stick together and form tissues. has also been shown to be involved in the regulation of cell survival, as it has been shown to play a role in the regulation of apoptosis, which is the process by which cells die.

PIM has also been shown to be involved in the regulation of DNA replication, which is the process by which a cell makes copies of its genetic material. PIM has been shown to play a crucial role in the regulation of DNA replication, as it has been shown to be involved in the formation of a protein complex on the replicating DNA molecule. This protein complex is known as the PIM-DNA complex, and it is involved in the regulation of DNA replication.

In addition to its role in cell signaling pathways, PIM has also been shown to have potential as a drug target. Its high conservation and various functions in cellular processes make it an attractive target for drug development.

One of the potential drug targets for PIM is its role in cell proliferation. inhibitors of PIM have been shown to have anti-proliferative effects, suggesting that they may be useful in the treatment of various cancers. Additionally, PIM has been shown to play a role in the regulation of cell differentiation and survival, which may make it an attractive target for drugs that are aimed at promoting or inhibiting these processes.

Another potential drug target for PIM is its role in cell signaling pathways. inhibitors of PIM have been shown to have effects on various cellular processes, including cell signaling, DNA replication, and cell cycle progression. These effects suggest that PIM may be involved in the regulation of various cellular processes, and that inhibitors of PIM may be useful in the treatment of various diseases.

In conclusion, PIM is a well-known protein that plays a crucial role in various cellular processes. Its function in cell signaling pathways, as well as its potential as a drug target, makes it an attractive target for further study and development. As research continues to advance, it is likely that new and innovative drugs will be developed that target PIM and its various functions.

Protein Name: Pim Kinase (nonspecified Subtype)

The "Pim Kinase Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about Pim Kinase comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets